Contact information
LOCATION:
Institute of Developmental and Regenerative Medicine, Old Road Campus, Oxford OX3 7TY
John Radcliffe Hospital, Level 6, Headley Way, Headington, Oxford, OX3 9DU
Colleges
Fadi Issa
DPhil FRCS(Plast)
Professor of Transplantation, Associate Head & Surgical Sciences Theme Lead
- Consultant Plastic, Reconstructive and Burns Surgeon
- Governing Body Fellow, Green Templeton College
- Academic Lead for Research Funding, Medical Sciences Division
I am Professor of Transplantation at the University of Oxford and a consultant surgeon. My work focuses on turning immunological insight into practical therapies that improve outcomes after organ and cell transplantation, and on broadening the use of immune targeted treatments in inflammatory and immune mediated disease. I integrate mechanistic immunology, biomarker and tissue based human studies, and early phase clinical trials, with a consistent emphasis on safety, durability, and real world implementation.
The Translational Research Immunology Group (TRIG) brings together graduate students, postdoctoral researchers, and clinical academics working across immunology, transplantation, tissue repair, and data driven translational science. We develop and test cellular and immunomodulatory therapies, and use deep immune profiling to understand mechanisms of response, resistance, and long term benefit. Our approach maintains a clear line of sight from discovery to patient impact.
Within Oxford, I serve as Associate Head of Department in the Nuffield Department of Surgical Sciences as Theme Lead for Surgical Sciences. I am also MSD Academic Lead for Research Funding and a Governing Body Fellow at Green Templeton College.
I am Editor in Chief of BMJ Immunology and an Executive Editor of Transplantation. I serve on the Steering Committee of FOCIS and previously chaired The Transplantation Society’s Transplantation Science Committee.
I am committed to building a rigorous and supportive training environment for early career researchers and clinicians, and welcome enquiries from prospective students, fellows, and collaborators.
Recent publications
Epigenetic modulation of stromal cell states underpins pathological tissue niches in Crohn's disease.
Journal article
Koplev S. et al, (2026), Nature immunology
Tolerance meets regenerative medicine: A new route to donor-specific allograft acceptance?
Journal article
Jull P. and Issa F., (2026), American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 26, 1519 - 1521
Toward Global Standards for Disaster Medical Specialists: A Scoping Review of Competencies for Emergency Medical Teams.
Journal article
Woodward CA. et al, (2026), Disaster medicine and public health preparedness, 20
People in Transplantation: Professor Nadey Hakim, MD, PhD, FRCS, FRCSGlas (Hon), FACS, President-Elect of The Transplantation Society.
Journal article
Issa F., (2026), Transplantation
Population Viral Load Suppression and Associated Factors in Tanzania: Findings From 2 Sequential Tanzania HIV Impact Surveys of 2016-2017 and 2022-2023.
Journal article
Ismail A. et al, (2026), Journal of acquired immune deficiency syndromes (1999), 101, 733 - 739
Clinical development of tacrolimus-resistant regulatory T cells to enable simultaneous immunosuppression and immune regulation.
Journal article
Zarrinrad G. et al, (2026), Molecular therapy. Advances, 34
Professor Jeremy R. Chapman, AC: Editor-in-Chief, The Transplantation Journals.
Journal article
Issa F., (2026), Transplantation, 110, e1161 - e1163
Anita Chong, PhD, Professor of Surgery, University of Chicago.
Journal article
Issa F. and Chong A., (2026), Transplantation
Protocol for a phase I single-centre dose escalation trial of autologous thymus derived regulatory T cells in paediatric heart transplant recipients to prevent cardiac allograft vasculopathy (ATT-Heart).
Journal article
Aiyengar A. et al, (2026), BMJ open, 16
Conventional type-1 DC density is associated with checkpoint inhibitor response across multiple types of cancer.
Journal article
Lopez-Janeiro A. et al, (2026), The Journal of clinical investigation, 136

